Avoid them. You have very dangerous stuff going on. Everybody should wearing safety glasses within the area. A ricocheting nail or exploding knot could be a life changer. Conifer knots tend to be violent exploders. You may try predrilling a hole if have to have a fastener in a knot. Protect yourself and coworkers, avoid knots. Having spent my life with one eye I can't express how important protection is. Everybody within several yards of that nail gun should have eye and ear protection. Move safe and live happily ever after. Good luck. And what are you doing with that nail gun in a timber frame shop?