As Andy suggests high velocity systems are a wonder to work with. The better ones use 2" diameter round flex for air distribution and can easigly be placed in room corners where they are unobtrusive and don't eat wall space. they can be routed directly from you air handler or from a secondary manifold about half a cubic foot in size per floor. They tend to be almost silent, no fan noise and move air at an astonishing 2000cfm. You may find the unicosystem.com website interesting. To go an even greater step forward make you heat exchanger geothermal and get the most energy out for the least energy inserted.
deralte