I did one using the ICFs as the exterior wall to the roof plates.
From there the roof was a conventional timber frame.
The interior posts were conventional as were all of the girts and floor trusses.
The only thing that wasn't truly load bearing were the perimeter posts. They looked like they were but there wasn't any true joinery connecting them to the plate
Heres a link. You can see the white ICF wall in the lower part of the picture. That area in the foreground was all loft. The area from the cameras perspective is all open to above.
http://echo7sphotos.photosite.com/HOMESUNDERCONSTRUCTION/Otterson/We designed it and raised the frame, the customer was the GC.